Blood test measuring 1,25-dihydroxyvitamin D, the active hormone form of vitamin D, used in specific calcium and kidney disorders.
- Medicare
- $0.00
- Work RVU
- 0
- Global, days
- Region
- General
Documentation requirements
What must appear in the operative or office note to support the claim.
Source · Editorial brief grounded in 3 cited references ↓
- Specific indication, such as hypercalcemia, CKD mineral bone disorder, or granulomatous disease
- Related lab results, such as calcium and PTH
- Reason the active form is needed instead of 25-hydroxyvitamin D
- Ordering provider and specialty
- Plan based on the result
Applicable modifiers
Modifiers commonly billed with this code.
Source · AMA CPT modifier descriptors · CMS NCCI Policy Manual
What this code covers
Source · Editorial summary grounded in 3 cited references ↓
Ordering 82652 to check vitamin D status is a mistake. It measures the active hormone. The deficiency test is 82306. The active form can read normal or even high in a deficient patient because the body ramps up conversion, so it misleads when used for status.
There are real uses: hypercalcemia workups, chronic kidney disease with bone and mineral disorder, sarcoidosis or other granulomatous disease, and certain rare rickets and phosphate disorders. An orthopedic surgeon might see it in a patient with unexplained high calcium found during a fracture workup, but the order usually comes from endocrinology or nephrology.
The most common denial for 82652 is the diagnosis mismatch: a vitamin D deficiency or osteoporosis code on a 1,25 order. Medicare contractor policies limit it to specific conditions. If your practice orders it by mistake for vitamin D status, the fix is to order 82306 instead, not to appeal.
RVU & reimbursement
Component RVUs and Medicare national rate. Actual payment varies by GPCI locality.
Source · CMS Physician Fee Schedule, RVU26A · January 2026
| Work RVU | 0 |
| Practice expense RVU | 0 |
| Malpractice RVU | 0 |
| Total RVU | 0 |
| Medicare national rate | $0.00 |
| Global period | days |
Payment by site of service
Medicare pays different rates by setting. HOPD typically pays substantially more than ASC for the same procedure.
Source · CMS OPPS Addendum B·ASC HCPCS payment rates·2026
| Setting | Medicare rate (national) |
|---|---|
Office (PFS non-facility) Procedure performed in physician's office | $0.00 |
Common denial reasons
The recurring reasons claims for CPT 82652 get rejected.
Source · Editorial brief grounded in CMS NCCI edits, AAOS coding appeals, and cited references ↓
- Ordered for routine vitamin D deficiency instead of 82306
- Osteoporosis or deficiency diagnosis on the claim
- Diagnosis not on the payer's covered list
- Ordered together with 82306 without separate justification
- Repeat sooner than policy allows
Frequently asked questions
Source · Generated from the editorial pipeline, verified against 3 cited references ↓
01Should I order 82652 to check vitamin D deficiency?
02What diagnoses support 82652?
03Why was my 1,25 vitamin D test denied?
Sources & references
Editorial content was developed using the following public sources.
Mira Scribe
Mira Scribe documents the calcium findings and related history in the note, which helps the coder confirm whether 1,25 or the standard vitamin D test was intended.
See how Mira captures CPT 82652 documentation