Sjogren syndrome

M35.00 identifies Sjögren syndrome where the documentation does not specify any associated organ or system manifestation — the default code when the clinical picture is confirmed Sjögren's but no organ-specific subtype is documented.

Sjögren syndrome with keratoconjunctivitis sicca — the specific subcode for Sjögren-related dry eye and corneal inflammation confirmed as autoimmune in etiology.

Sjögren syndrome with documented pulmonary manifestations, classified under systemic connective tissue disorders in ICD-10-CM Chapter 13.

Sjögren syndrome with documented skeletal muscle involvement (myopathy), classified under systemic connective tissue disorders in ICD-10-CM Chapter 13.

Sjögren syndrome with renal tubulo-interstitial involvement, capturing the specific manifestation of tubulointerstitial nephropathy — including renal tubular acidosis — as a direct complication of the systemic autoimmune disease.

Sjögren syndrome presenting with inflammatory arthritis as a documented systemic manifestation, classified under the M35.0 Sjögren syndrome family of codes.

M35.06 identifies Sjögren syndrome in which the autoimmune process has extended to involve the peripheral nervous system, such as sensory neuropathy, sensorimotor polyneuropathy, or autonomic neuropathy, as a documented systemic manifestation.

Sjögren syndrome with documented involvement of the central nervous system, including brain, spinal cord, or meninges manifestations attributable to the underlying autoimmune disease.

Sjögren syndrome presenting with documented gastrointestinal tract involvement, classified under systemic connective tissue disorders (M35.0x family).

M35.09 captures Sjögren syndrome when the organ involvement doesn't match any of the more specific M35.0x codes — a true residual category for documented systemic manifestations outside the named subcategories.

Sjögren syndrome with documented glomerular disease as a systemic manifestation — a specific subset of M35.0 reserved for cases where renal glomerular involvement is clinically established.

M35.0B identifies Sjögren syndrome in which vasculitis — inflammation of blood vessel walls — has been documented as an associated systemic manifestation of the underlying autoimmune disease.

M35.0C identifies Sjögren syndrome when the documented manifestation is dental involvement — specifically the oral and salivary gland effects of this systemic autoimmune condition, such as xerostomia-driven rampant caries, salivary gland dysfunction, or parotid enlargement.